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Major Research Areas


1. Small and Macro molecule X-ray Crystallography 2. 3D Quantitative structure - activity relationship
3. Human Molecular Genetics 4. Pharmacogenomics
5. Cheminformatics 6. Quantum Pharmacology
7. Computer Aided Drug Designing 8. Aquaculture Biotechnology
9. Data mining & warehousing 10. Plant Bioinformatics
11. Nano Drug Delivery 12. Molecular Oncology & Environment Toxicology

Research funds from various agencies


S. No. Principle Investigator Title Funding Agencies Amount (Rs. in lakhs) Duration
1. Sanjeev Kumar Singh Computational Screening of CDK2 Inhibitors by Combined approach of Pharmacophoric study, QPLD and Molecular Dynamics Simulation analysis DST Fast Track 18.95 2011-14
2. M. Karthikeyan Genetic polymorphisms of the essential hypertension associated genes in random subjects of the South Indian general population UGC 13.31 2010-13
3. P. Srinivasan Genome characterization and molecular docking of Bacillus phages and their inhibitory effects against shrimp pathogenic bacteria TNSCST 1.892 2009-12
4. Sanjeev Kumar Singh Pharmacophoric analysis and designing of ATP competitive CDK 4 inhibitors AURF 4 .00 2010-13
5. M. Karthikeyan Investigation of binding of HA Protein with sialic acid ligand base lead identification of neuraminidase inhibitor of H1N1 2009 influenza virus CSIR 15.98 2011-14
6. A. Sudha (Research Scholar) Biological evaluation and in silico analysis of …… DST WOSA 15.36 2011-14
7. P. Srinivasan Molecular characterization, molecular docking and biocontrol effect of Vibrio bacteriophages from shrimp aquaculture environment UGC 7.64 2011-14
8. Sanjeev Kumar Singh Shape and chemical feature based 3D- Pharmacophore Model generation, Virtual Screening and MESP studies to identify Potential Leads for Antifungal Azoles. UGC 7.48 2011-14
9. Sanjeev Kumar Singh QM/MM partial charges, binding pocket contours analysis and FEP calculation for designing potent inhibitors of HTLV- Protease: A de novo drug design approach CSIR 16.02 2012-15
10. J. Jeyakanthan Structural and Functional analysis of Orotate Phosphoribosyl transferase (TTHA1742) and Dihydroorotate Dehydrogenase (TTHA0779) from Thermus thermophilus HB8 DBT 50.25 2012-15
11. J. Jeyakanthan Structure and functional studies on PH0140 protein from Pyrococcus horikoshii OT3 UGC 12.90 2012-15
12. P. Srinivasan Development of Microarray for the detection of Bacteria / Bacteriophages and controlling measures against pathogenic bacteria from shrimp aquaculture environment DST Fast Track 23.44 2012-15
13. J. Jeyakanthan Structure determination of CPS and ATCase of Thermus thermophilus HB8 and identification of potential inhibitors DBT 32.16 2012-15
14. J. Jeyakanthan Structural and Functional Studies of Translation Initiation factors from Pyrococcus horikoshii OT3 DBT-Twin 77.00 2013-16
15. J. Jeyakanthan Structural and Functional Studies of Purine Biosynthesis complex from Pyrococcus horikoshii OT3 DST 48.98 2013-16
16. Sanjeev Kumar Singh Identification of novel drug targets of Leishmania donovani: Studies on CAAX prenyl protease I and II of the pathogen DBT-Twin 73.69 2014-17
17. M. Karthikeyan Pharmacogenomics Study of Anti Hypertensive Treatment in South Indian Population ICMR 21.15 2014-17
18. J. Jeyakanthan Development of Web Based Search Engines for the Analyses of Protein interactions with Nucleotides, Fatty Acids and Buffers DBT 13.81 2015-18
19. J. Jeyakanthan (Coordinator) UGC Innovative PG. Diploma on Structural Pharmacogenomics UGC 54.00+ 2 Asst. Professors 2013-18
20. Dr. Sanjeev Kumar Singh In silico screening, theoretical calculation and in vitro studies for development of potential HIV1-PR inhibitors DBT 19.51 2016-19
21. Dr. M. Karthikeyan Computational identification and in vitro validation of small molecule inhibitors for tankyrase protein to inhibit the over expression of Wnt/ß-catenin signalling mechanism using HCA-7, HCT116 and MDST8/ HCA-46 colon cancer cell lines: A new drug target for Colorectal Cancer DBT 30.48 2016-19
22. J. Jeyakanthan Identification of Potential Anti-Filiarial drug targeted enzymes Wbm0441, Wbm0042 from Wolbachia endosymbiont Brugia malayi DST 69.38 2016-19
23. Dr. RM. Vidhyavathi Classification of hierarchical clustering with FP-Growth algorithm to analyzing and creating the solution for Chromosomal disorder AURF 0.80 2016-18


MoU with Overseas Institutes & Universities


S. No. International / National Period
1. Biometal Science Dept, RIKEN, Harima Institute, Japan & SPring-8, Japan 2010-15
2. Institute of Protein Research, Osaka University, Japan 2010-15
3. RIKEN, Kanagawa, Japan 2010-15
4. School of Science, Osaka University, Japan 2010-15
5. National Synchrotron Radiation Research Center (NSRRC), Taiwan 2014-17
6. Nanyang Technological University, School of Biological Sciences, Singapore (Dst Indo-Singapore Joint Project Loi Established) 2014-17
7. CSIR-Central Drug Research Institute, Lucknow 2014-17
8. Sri Ramachandra University, Chennai 2016-21
9. IIT Madras, Chennai 2016-21

Research Collaborations


S.No. INDIA (COLLABORATION WITH INDIAN UNIVERSITIES) S.No. OVERSEAS (COLLABORATIONS WITH OVERSEAS)
1. Indian Institute of Science, Bangalore 1. Nanyang Technological University for Research, Singapore
2. University of Madras, Chennai 2. National Synchrotron Radiation Research Center, Taiwan
3. Chhatrapati ShahuJi Maharaj University, Kanpur 3. RIKEN, Harima Institute of Japan, Japan
4. Institute of Life Sciences, Bhubaneswar 4. National Institute of Biomedical Innovation, Osaka, Japan
5. Madurai Kamaraj University, Madurai 5. Loma Linda University, Loma Linda, California
6. Pondicherry University, Puducherry 6. Addis Ababa University, Ethiopia
7. IIT Guwahati, Assam
8. ICGEB, New Delhi
9. CSIR - Central Electrochemical Chemical Research Institute, Karaikudi
10. SASTRA University, Thanjavur